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ABSORPTION
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paracellular drug diffusion:a process that go through gaps or tight junctions between cells.
digestion:the breakdown of food constituents into smaller structures in preparation for absorption.
rectum:ending at the anus; has a small amount of fluid (approximately 2 mL) with a pH of about 7.
transcellular transport:the process of drug movement across a cell.
active transport:a carrier-mediated transmembrane process that plays an important role in the GIT absorption and in renal and biliary secretion of many drugs and metabolites.
gastrin:is released from G cells, mainly in the antral mucosa and also in the duodenum.
duodenum:it is the major area of absorption.
passive diffusion:the major absorption process for most drugs.
saliva:the main secretion of the oral cavity.
GI motility:it tends to move the drug through the alimentary canal, so the drug may not stay at the absorption site.
phagocytosis:it refers to the engulfment of larger particles macromolecules, generally by macrophages.
jejunum:it is preferred for in vivo drug absorption studies
stomach pH:it may be increased due to the presence of food and certain drugs such as omeprazole.
stomach:it is innervated by the vagus nerve.
stomach acid secretion:it is stimulated by gastrin and histamine.
lipid bilayer:theory that considers the plasma membrane to be composed of two layers of phospholipid between two surface layers of proteins.
absorption:it is the passage of a drug from its site of administration to systemic circulation.
ileum:the terminal part of the small intestine.
colon: it tracks villi and has limited drug absorption.
mucin:a glycoprotein that lubricates food.
ABSORPTION
Across:1. | theory that considers the plasma membrane to be composed of two layers of phospholipid between two surface layers of proteins. | 3. | a process that go through gaps or tight junctions between cells. | 4. | it is the passage of a drug from its site of administration to systemic circulation. | 8. | the major absorption process for most drugs. | 10. | the breakdown of food constituents into smaller structures in preparation for absorption. | 11. | it is innervated by the vagus nerve. | 13. | it tracks villi and has limited drug absorption. | 17. | it is stimulated by gastrin and histamine. | 18. | the terminal part of the small intestine. |
| | Down:2. | a carrier-mediated transmembrane process that plays an important role in the GIT absorption and in renal and biliary secretion of many drugs and metabolites. | 3. | it refers to the engulfment of larger particles macromolecules, generally by macrophages. | 5. | it is the major area of absorption. | 6. | a glycoprotein that lubricates food. | 7. | it is preferred for in vivo drug absorption studies | 9. | it may be increased due to the presence of food and certain drugs such as omeprazole. | 12. | it tends to move the drug through the alimentary canal, so the drug may not stay at the absorption site. | 14. | is released from G cells, mainly in the antral mucosa and also in the duodenum. | 15. | the main secretion of the oral cavity. | 16. | ending at the anus; has a small amount of fluid (approximately 2 mL) with a pH of about 7. |
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© 2015
PuzzleFast.com, Noncommercial Use Only
ABSORPTION
Across:1. | theory that considers the plasma membrane to be composed of two layers of phospholipid between two surface layers of proteins. | 3. | a process that go through gaps or tight junctions between cells. | 4. | it is the passage of a drug from its site of administration to systemic circulation. | 8. | the major absorption process for most drugs. | 10. | the breakdown of food constituents into smaller structures in preparation for absorption. | 11. | it is innervated by the vagus nerve. | 13. | it tracks villi and has limited drug absorption. | 17. | it is stimulated by gastrin and histamine. | 18. | the terminal part of the small intestine. |
| | Down:2. | a carrier-mediated transmembrane process that plays an important role in the GIT absorption and in renal and biliary secretion of many drugs and metabolites. | 3. | it refers to the engulfment of larger particles macromolecules, generally by macrophages. | 5. | it is the major area of absorption. | 6. | a glycoprotein that lubricates food. | 7. | it is preferred for in vivo drug absorption studies | 9. | it may be increased due to the presence of food and certain drugs such as omeprazole. | 12. | it tends to move the drug through the alimentary canal, so the drug may not stay at the absorption site. | 14. | is released from G cells, mainly in the antral mucosa and also in the duodenum. | 15. | the main secretion of the oral cavity. | 16. | ending at the anus; has a small amount of fluid (approximately 2 mL) with a pH of about 7. |
| |
© 2015
PuzzleFast.com, Noncommercial Use Only