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Immunology Crossword Puzzle
9
MHC:A group of genes encoding cell-surface molecules that are required for antigen presentation to T cells and for rapid graft rejection.
Class I:The set of genes that encode class I MHC molecules, which are glycoproteins found on nearly all nucleated cells.
Class II:Heterodimeric membrane proteins; They are expressed by nearly all nucleated cells and function to present antigen to CD8+ T cells.
Endogenous:Intracellular route taken by antigen that is processed for presentation by MHC class I, typically associated with proteins generated in the cytosol.
Exogenous:Intracellular route taken by antigen that is processed for presentation by MHC class II, typically associated with proteins that are endocytosed.
Double Positive:A subset of developing T cells (thymocytes) that express both CD4 and CD8.
Tapsin:TAP-associated protein.
Apoptosis:A process where cells initiate a signaling pathway that results in their own demise.
Calreticulin:A protein resident of the ER that serves, along with calnexin, as a molecular chaperone to assist in class I MHC molecule assembly.
Self MHC Restriction:The property of recognizing antigenic peptides only in the context of self MHC molecules.
Immunology Crossword Puzzle
Across:| 1. | Intracellular route taken by antigen that is processed for presentation by MHC class I, typically associated with proteins generated in the cytosol. | | 3. | A subset of developing T cells (thymocytes) that express both CD4 and CD8. | | 5. | The set of genes that encode class I MHC molecules, which are glycoproteins found on nearly all nucleated cells. |
| | 6. | Intracellular route taken by antigen that is processed for presentation by MHC class II, typically associated with proteins that are endocytosed. | | 7. | A protein resident of the ER that serves, along with calnexin, as a molecular chaperone to assist in class I MHC molecule assembly. | | 8. | A process where cells initiate a signaling pathway that results in their own demise. |
| | Down:| 2. | The property of recognizing antigenic peptides only in the context of self MHC molecules. | | 4. | TAP-associated protein. |
| | 5. | Heterodimeric membrane proteins; They are expressed by nearly all nucleated cells and function to present antigen to CD8+ T cells. |
| |
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PuzzleFast.com, Noncommercial Use Only
Immunology Crossword Puzzle
Across:| 1. | Intracellular route taken by antigen that is processed for presentation by MHC class I, typically associated with proteins generated in the cytosol. | | 3. | A subset of developing T cells (thymocytes) that express both CD4 and CD8. | | 5. | The set of genes that encode class I MHC molecules, which are glycoproteins found on nearly all nucleated cells. |
| | 6. | Intracellular route taken by antigen that is processed for presentation by MHC class II, typically associated with proteins that are endocytosed. | | 7. | A protein resident of the ER that serves, along with calnexin, as a molecular chaperone to assist in class I MHC molecule assembly. | | 8. | A process where cells initiate a signaling pathway that results in their own demise. |
| | Down:| 2. | The property of recognizing antigenic peptides only in the context of self MHC molecules. | | 4. | TAP-associated protein. |
| | 5. | Heterodimeric membrane proteins; They are expressed by nearly all nucleated cells and function to present antigen to CD8+ T cells. |
| |
© 2016
PuzzleFast.com, Noncommercial Use Only