1DegreeBio's Epigenetic Crossword
a crossword puzzle by
PuzzleFast Instant Puzzle Maker
Puzzle URL
https://www.puzzlefast.com/en/puzzles/20120604095780
To embed this puzzle on your website, paste the markup below into your HTML. Change the width and height values as desired.
Plain Puzzle
Plain Puzzle Without Solution Link
Hide This
1:00
en
CR
1DegreeBio's Epigenetic Crossword
31
Epigenome: chemical changes to the DNA and histones of an organism - think big!
Methylation: covalent DNA modification that represses transcription
HAT: an enzyme that acetylates lysine on histone proteins, or an item of clothing (acronym)
HDAC: an enzyme that removes acetyl groups from histone proteins (acronym)
Denovo: “from the beginning” in latin (two words)
Maintenance: DNMT1 is the __________ DNA methyltransferase
octamer: H2a, H2b, H3, H4 (twice)
ChIP: a technique used to study protein - chromatin interaction (acronym)
MeDIP: a technique used to separate methylated from non-methylated DNA (acronym)
Hydroxymethylcytosine: the 6th base pair (without the 5-)
Histones: basic proteins commonly associated with DNA, can be “core” or “linker”
Beadsonastring: what you see under an electron microscope when DNA wraps around histone proteins forming nucleosomes, or a bracelet (4 words)
Noncoding: long ________ RNA
XIST: RNA that plays an important role in X-chromosome inactivation (acronym)
Polycomb: this complex mediates the addition of the methyl groups in H3K27me3
Trithorax: this group of proteins activates the Hox genes during development
Progeria: a rare genetic condition that produces rapid aging in children, associated with a mutated version of nuclear lamin A
Rettsyndrome: a neurodevelopmental disorder caused by mutations in the MECP2 gene located on the X chromosome (2 words)
Imprinting: the process of expressing genes in a parent of origin specific manner, ie. H19 and IGF2 loci
Bioinformatics: application of computer science and IT to biology, especially with huge data sets
Promoter: a region of DNA that facilitates the transcription of a particular gene, it may be TATA-less
CpGisland: a genomic region that contain a high frequency of cytosines and guanines (2 words)
Intergenic: a stretch of DNA located between genes that contain few or no genes
Centromere: where sister chromatids meet
Telomere: the end of a chromosome
Transcription factor: a protein that binds to specific DNA sequences (2 words)
Heterochromatin: tightly coiled, transcriptionally inactive DNA
Reprogramming: erasure and remodeling of epigenetic marks that occurs during mammalian development of germ cells and as fibroblasts are turned into iPS cells
Monozygotic: identical (twins), originating from a single egg
somatic: ____ cell nuclear transfer involves the transfer of a nucleus from one cell to the cytoplasm of an enucleated egg
sodiumbisulfite: a chemical that deaminates cytosine into uracil, but does not affect methylated cytosines (2 words)
MSPI: a restriction enzyme, the isoschizomer of HpaII
1DegreeBio's Epigenetic Crossword
Across:4. | a technique used to separate methylated from non-methylated DNA (acronym) | 5. | tightly coiled, transcriptionally inactive DNA | 8. | “from the beginning” in latin (two words) | 9. | a protein that binds to specific DNA sequences (2 words) | 11. | this group of proteins activates the Hox genes during development | 14. | a chemical that deaminates cytosine into uracil, but does not affect methylated cytosines (2 words) |
| 15. | application of computer science and IT to biology, especially with huge data sets | 17. | a region of DNA that facilitates the transcription of a particular gene, it may be TATA-less | 20. | DNMT1 is the __________ DNA methyltransferase | 27. | a neurodevelopmental disorder caused by mutations in the MECP2 gene located on the X chromosome (2 words) | 28. | the process of expressing genes in a parent of origin specific manner, ie. H19 and IGF2 loci | 30. | a stretch of DNA located between genes that contain few or no genes |
| | Down:1. | an enzyme that acetylates lysine on histone proteins, or an item of clothing (acronym) | 2. | an enzyme that removes acetyl groups from histone proteins (acronym) | 3. | what you see under an electron microscope when DNA wraps around histone proteins forming nucleosomes, or a bracelet (4 words) | 6. | the 6th base pair (without the 5-) | 7. | ____ cell nuclear transfer involves the transfer of a nucleus from one cell to the cytoplasm of an enucleated egg | 10. | H2a, H2b, H3, H4 (twice) | 12. | a technique used to study protein - chromatin interaction (acronym) | 13. | erasure and remodeling of epigenetic marks that occurs during mammalian development of germ cells and as fibroblasts are turned into iPS cells | 16. | identical (twins), originating from a single egg | 18. | chemical changes to the DNA and histones of an organism - think big! |
| 19. | long ________ RNA | 20. | covalent DNA modification that represses transcription | 21. | where sister chromatids meet | 22. | a genomic region that contain a high frequency of cytosines and guanines (2 words) | 23. | a rare genetic condition that produces rapid aging in children, associated with a mutated version of nuclear lamin A | 24. | the end of a chromosome | 25. | this complex mediates the addition of the methyl groups in H3K27me3 | 26. | basic proteins commonly associated with DNA, can be “core” or “linker” | 29. | RNA that plays an important role in X-chromosome inactivation (acronym) |
| |
© 2012
PuzzleFast.com, Noncommercial Use Only
1DegreeBio's Epigenetic Crossword
Across:4. | a technique used to separate methylated from non-methylated DNA (acronym) | 5. | tightly coiled, transcriptionally inactive DNA | 8. | “from the beginning” in latin (two words) | 9. | a protein that binds to specific DNA sequences (2 words) | 11. | this group of proteins activates the Hox genes during development | 14. | a chemical that deaminates cytosine into uracil, but does not affect methylated cytosines (2 words) |
| 15. | application of computer science and IT to biology, especially with huge data sets | 17. | a region of DNA that facilitates the transcription of a particular gene, it may be TATA-less | 20. | DNMT1 is the __________ DNA methyltransferase | 27. | a neurodevelopmental disorder caused by mutations in the MECP2 gene located on the X chromosome (2 words) | 28. | the process of expressing genes in a parent of origin specific manner, ie. H19 and IGF2 loci | 30. | a stretch of DNA located between genes that contain few or no genes |
| | Down:1. | an enzyme that acetylates lysine on histone proteins, or an item of clothing (acronym) | 2. | an enzyme that removes acetyl groups from histone proteins (acronym) | 3. | what you see under an electron microscope when DNA wraps around histone proteins forming nucleosomes, or a bracelet (4 words) | 6. | the 6th base pair (without the 5-) | 7. | ____ cell nuclear transfer involves the transfer of a nucleus from one cell to the cytoplasm of an enucleated egg | 10. | H2a, H2b, H3, H4 (twice) | 12. | a technique used to study protein - chromatin interaction (acronym) | 13. | erasure and remodeling of epigenetic marks that occurs during mammalian development of germ cells and as fibroblasts are turned into iPS cells | 16. | identical (twins), originating from a single egg | 18. | chemical changes to the DNA and histones of an organism - think big! |
| 19. | long ________ RNA | 20. | covalent DNA modification that represses transcription | 21. | where sister chromatids meet | 22. | a genomic region that contain a high frequency of cytosines and guanines (2 words) | 23. | a rare genetic condition that produces rapid aging in children, associated with a mutated version of nuclear lamin A | 24. | the end of a chromosome | 25. | this complex mediates the addition of the methyl groups in H3K27me3 | 26. | basic proteins commonly associated with DNA, can be “core” or “linker” | 29. | RNA that plays an important role in X-chromosome inactivation (acronym) |
| |
© 2012
PuzzleFast.com, Noncommercial Use Only